CVE-2026-31966

Published: Mar 18, 2026 Last Modified: Mar 18, 2026
ExploitDB:
Other exploit source:
Google Dorks:
MEDIUM 6,9
Attack Vector: network
Attack Complexity: low
Privileges Required: none
User Interaction: none
Confidentiality: N/A
Integrity: N/A
Availability: N/A

Description

AI Translation Available

HTSlib is a library for reading and writing bioinformatics file formats. CRAM is a compressed format which stores DNA sequence alignment data. As one method of removing redundant data, CRAM uses reference-based compression so that instead of storing the full sequence for each alignment record it stores a location in an external reference sequence along with a list of differences to the reference at that location as a sequence of 'features'. When decoding CRAM records, the reference data is stored in a char array, and parts matching the alignment record sequence are copied over as necessary. Due to insufficient validation of the feature data series, it was possible to make the `cram_decode_seq()` function copy data from either before the start, or after the end of the stored reference either into the buffer used to store the output sequence for the cram record, or into the buffer used to build the SAM `MD` tag. This allowed arbitrary data to be leaked to the calling function. This bug may allow information about program state to be leaked. It may also cause a program crash through an attempt to access invalid memory. Versions 1.23.1, 1.22.2 and 1.21.1 include fixes for this issue. There is no workaround for this issue.

125

Out-of-bounds Read

Draft
Common Consequences
Security Scopes Affected:
Confidentiality Availability Other
Potential Impacts:
Read Memory Bypass Protection Mechanism Dos: Crash, Exit, Or Restart Varies By Context
Applicable Platforms
Languages: C, C++, Memory-Unsafe
Technologies: ICS/OT
View CWE Details
129

Improper Validation of Array Index

Draft
Common Consequences
Security Scopes Affected:
Integrity Availability Confidentiality
Potential Impacts:
Dos: Crash, Exit, Or Restart Modify Memory Read Memory Execute Unauthorized Code Or Commands
Applicable Platforms
Languages: C, C++, Not Language-Specific
View CWE Details
https://github.com/samtools/htslib/commit/22ec5230ef95769ab009420da69568c7e530a…
https://github.com/samtools/htslib/commit/2a45eb129d703ad27f9fabc8169f0e94d3c69…
https://github.com/samtools/htslib/commit/4a5ef25eb1fb3d64438103316fffe423b2c3f…
https://github.com/samtools/htslib/security/advisories/GHSA-5cj8-mj52-8vp3